Efficient Havinga–Kondepudi resolution of conglomerate amino acid derivatives by slow cooling and abrasive grinding
Michel Leeman, Wim L. Noorduin, Alessia Millemaggi, Elias Vlieg, Hugo Meekes, Willem J. P. van Enckevort, Bernard Kaptein and Richard M. Kellogg
CrystEngComm, 2010, 12, 2051-2053
racemization conglomerate
The complete resolution of the conglomerate racemates of two amino acid derivatives susceptible to racemization in solution was achieved by slow crystallization from a supersaturated solution accompanied by cooling and abrasive grinding.