Hydration and
Dehydration of the Pure Enantiomer and the Racemic of Phencyphos
F. Querniard1, M. Leeman, Y. Cartigny, R.M. Kellogg, E. Vlieg and G.
Coquerel
Abstract:
This study is devoted to the understanding of phencyphos
hydration/dehydration behaviour. Phencyphos is a resolving agent used
in the so-called Dutch resolution. Batches of phencyphos contain
various amounts of water (from 0 to 1 equivalent of water) evolving
over time, inducing wrong dosages. Phase diagrams between phencyphos,
water and methanol or ethanol were determined. Then, solid phases were
characterized and compared with the means of X-ray Powder Diffraction,
InfraRed spectroscopy, Differential Scanning Calorimetry and Dynamic
Vapour Sorption. All these experiments have led to reliable conversion
methods and storage conditions.