Emergence of a single solid chiral state from a nearly racemic amino acid derivative
Noorduin WL , Izumi T, Millemaggi A , Leeman M , Meekes H , Van Enckevort WJP , Kellogg RM , Kaptein B, Vlieg E , Blackmond DG
J. Am. Chem. Soc.130 no. 4 (2008) 1158-1159

Abstract:
The evolution of a single chiral solid state is reported for an amino acid derivative starting from a nearly racemic mixture of solid left- and right-handed crystals. Attrition-enhanced dissolution and recrystallization processes based on solubility considerations of the Gibbs-Thomson rule, coupled with solution-phase racemization, drive this near-equilibrium system inexorably to single chirality in the solid phase.