Abstract:
The growth morphology of monoclinic paracetamol as a function of the
supersaturation is determined using Monte Carlo simulations based on the
crystal structure. The results are compared with experimental results reported
recently on both the morphology and the relevant growth mechanisms. The
change of an elongated to a more bulky habit with increasing supersaturation
is reproduced well by the simulations. The method used opens ways to predict
the crystal morphology for real crystal structures in, dependence of supersaturation
once information on the relevant growth mechanism for the various faces
is known.